Pureum Jeon, Manbok Choi, Jungju Oh, and Minhyung Lee (2015) Dexamethasone-conjugated polyamidoamine dendrimer for delivery of the heme oxygenase-1 gene into the ischemic brain. Macromol. Biosci. 15(7): 1021-1028.
Hyun Ah Kim, Hyun-Lin Lee, Eunji Choi, Yong-Hee Kim, and Minhyung Lee (2015) Reducible poly(oligo-D-arginine) as an efficient carrier of the thymidine kinase gene in the intracranial glioblastoma animal model. J. Pharm. Sci. 104: 3743-3751.
Jin Hyeong Park, Jaesik Han, and Minhyung Lee (2015) Thymidine kinase gene delivery using curcumin loaded peptide micelles as a combination therapy for glioiblastoma. Pharm. Res. 32(2):528-537.
Hojung Song, Binna Oh, Manbok Choi, Jungju Oh, and Minhyung Lee (2015) Delivery of anti-microRNA-21 antisense-oligodeoxynucleotide using amphiphilic peptides for glioblastoma gene therapy. J. Drug Target. 23(4): 360-370.
Binna Oh, Jaesik Han, Eunji Choi, Xiaonan Tan, and Minhyung Lee (2015) Peptide Micelle-Mediated Delivery of Tissue-Specific Suicide Gene and Combined Therapy with Avastin in a Glioblastoma Model. J. Pharm. Sci. 104(4): 1461-1467.
Hyo-Jeong Hwang#, Minhyung Lee#, Jin Hyeong Park, Hye Seung Jung, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, and Sung-Hee Ihm (2015) Improved islet transplantation outcome by the co-delivery of siRNAs for iNOS and 17β-estradiol using an R3V6 peptide carrier. Biomaterials 38: 36-42 (#Co-first author)
Youngsang You, Lihua Che, Hye Yeong Lee, Hye-Lan Lee, Yeomin Yun, Minhyung Lee, Jinsoo Oh, and Yoon Ha (2015) Antiapoptotic effect of highly secreted GMCSF from neuronal cell-specific GMCSF overexpressing neural stem cells in spinal cord injury model. Spine 40(24): E1284-E1291.
Jongsu Woo, Seong-Ho Bae, Bokyoung Kim, Jin Sil Park, Subin Jung, Minhyung Lee, Yong-Hee Kim, and Donghoon Choi (2015) Cardiac usage of reducible poly(oligo-D-arginine) as a gene carrier for vascular endothelial growth factor expression. PLOS one 10(12):e0144491
Hye-Lan Lee, Jinsoo Oh, Yeomin Yun, Yeong Lee, Youngsang You, Lihua Che, Minhyung Lee, Keung Nyun Kim, and Yoon Ha (2015) Vascular endothelial growth factor-expressing neural stem cell for the treatment of neuropathic pain. Neuroreport 26(7): 399-404.
Jinsoo Oh, Yongsang You, Yeomin Yun, Hye-Lan Lee, Do Heum Yoon, Minhyung Lee, and Yoon Ha (2015) A gene and neural stem cell therapy platform based on neuronal cell type-inducible gene overexpression. Yonsei Med. J. 56(4): 1036-1043.
Hyun Ah Kim, Jin Hyeong Park, Na Yi, and Minhyung Lee (2014) Delivery of hypoxia and glioma dual-specific suicide gene using dexamethasone conjugated polyethylenimine for glioblastoma-specific gene therapy. Mol. Pharm. 11(3): 938-950.
Binna Oh and Minhyung Lee (2014) Combined delivery of HMGB-1 box A peptide and S1PLyase siRNA in animal models of acute lung injury. J. Control. Release 175: 25-35.
Na Yi, Binna Oh, Hyun Ah Kim, and Minhyung Lee (2014) Combined delivery of BCNU and VEGF siRNA using amphiphilic peptides for glioblastoma. J. Drug Target. 22(2): 156-164.
Bora Kim, Ji Hyun Song, and Minhyung Lee (2014) Combination of TAT-HMGB1A and R3V6 amphiphilic peptide for plasmid DNA delivery with anti-inflammatory effect. J. Drug Target. 22(8): 739-747.
Na Yi and Minhyung Lee (2014) Peptide micelles for anti-cancer drug delivery in an intracranial Glioblastoma animal model. Bull. Kor. Chem. Soc. 35(10): 3030-3034
Ji Won Park, Sook Hee Ku, Hyung-Ho Moon, Minhyung Lee, Donghoon Choi, Jaemoon Yang, Yong-Min Huh, Ji Hoon Jeong, Tae Gwan Park, Hyejung Mok, Sun Hwa Kim (2014) Cross-linked Iron Oxide Nanoparticles for Therapeutic Engineering and in Vivo Monitoring of Mesenchymal Stem Cells in Cerebral Ischemia Model. Macromol. Biosci. 14(3): 380-389.
Hyung-Ho Moon, Min Kyung Joo, Hyejung Mok, Minhyung Lee, Ki-Chul Hwang, Sung Wan Kim, Ji Hoon Jeong, Donghoon Choi, and Sun Hwa Kim (2014) MSC-based VEGF gene therapy in rat myocardial infarction model using facial amphipathic bile acid-conjugated polyethylenimine. Biomaterials 35(5): 1744–1754.
Taiyoun Rhim, Dong Yun Lee, and Minhyung Lee (2013) Hypoxia as a target for tissue specific gene therapy. J. Control. Release 172(2): 484-494.
Hyesun Hyun, Kyuri Lee, Kyung Hyun Min, Pureum Jeon, Kwangmeyoung Kim, Seo Young Jeong, Ick Chan Kwon, Tae Gwan Park, and Minhyung Lee (2013) Ischemic brain imaging using fluorescent gold nanoprobes sensitive to reactive oxygen species. J. Control. Release 170(3): 352-357.
Taiyoun Rhim, Dong Yun Lee, and Minhyung Lee (2013) Drug delivery systems for the treatment of ischemic stroke. Pharm. Res. 30(10): 2429-2444.
Jaehwan Ryu, Pureum Jeon, and Minhyung Lee (2013) R3V6 Amphiphilic Peptide with High Mobility Group Box 1A Domain as an Efficient Carrier for Gene Delivery. Bull. Kor. Chem. Soc. 34(12): 3665-3670.
Suhee Cho, Binna Oh, Hyun Ah Kim, Ji Hwan Park, and Minhyung Lee (2013) Post-translational regulation of gene expression using the ATF4 oxygen-dependent degradation domain for hypoxia-specific gene therapy. J. Drug Target. In press. 21(9): 830-836.
Dong Yun Lee, Taiyoun Rhim, and Minhyung Lee (2013) Cancer cell respiration: Hypoxia and pH in solid tumors. In Cancer Targeted Drug Delivery (Ed: Y.H. Bae, R.J. Mrsny, and K. Park) Springer, New York, pp. 183-206.
Hyun Ah Kim, Kihoon Nam, Minhyung Lee*, and Sung Wan Kim (2013) Hypoxia/hepatoma dual specific suicide gene expression plasmid delivery using bio-reducible polymer for hepatocellular carcinoma therapy. J. Control. Release 171(1): 1-10 (*Corresponding author).
Hee Young Chae1, Minhyung Lee1, Hyo Jeong Hwang, Hyun Ah Kim, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, and Sung-Hee Ihm* (2013) Improved transplantation outcome through delivery of DNA encoding secretion signal peptide-linked glucagon-like peptide-1 into mouse islets. Transplant. Int. 26(4): 443-452. (1Co-first author)
Young Wook Won, Minhyung Lee, Hyun Ah Kim, Kihoon Nam, David A. Bull, and Sung Wan Kim (2013) Synergistically combined gene delivery for enhanced VEGF secretion and antiapoptosis. Mol. Pharm. 10(10): 3676-3683.
Jun-Beom Park, Jee-Heon Jeong, Minhyung Lee, Dong Yun Lee, and Youngro Byun (2013) Xenotransplantation of exendin-4 gene transduced pancreatic islets using multi-component (alginate, poly-L-lysine, and polyethylene glycol) microcapsules for the treatment of type 1 diabetes mellitus. J. Biomater. Sci. Polym. Ed. 24(18): 2045-2057.
Youngsook Lee, Arlo N. McGinn, Curtis D. Olsen, Kihoon Nam, Minhyung Lee, Sug Kyun Shin, and Sung Wan Kim (2013) Human erythropoietin gene delivery for cardiac remodeling of myocardial infarction in rats. J. Control. Release 171(1): 24-32.
Young Wook Won, Arlo N. McGinn, Minhyung Lee, Kihoon Nam, David A. Bull, and Sung Wan Kim (2013) Post-translational regulation of a hypoxia-responsive VEGF plasmid for the treatment of myocardial ischemia. Biomaterials 34(26): 6229-6238.
Young Wook Won, Arlo N. McGinn, Minhyung Lee, David A. Bull, and Sung Wan Kim (2013) Targeted gene delivery to ischemic myocardium by homing peptide-guided polymeric carrier. Mol. Pharm. 10(1): 378-385.
Young Wook Won, Minhyung Lee, Hyun Ah Kim, David A. Bull, and Sung Wan Kim (2013) Hypoxia-inducible plasmid expressing both miSHP-1 and HO-1 for the treatment of ischemic disease. J. Control. Release 165(1): 22-28.
Pyung Hwan Kim, Minhyung Lee, Kihoon Nam, and Sung Wan Kim (2013) Enhanced Incretin Effects of Exendin-4 Expressing Chimeric Plasmid Based On Two-Step Transcription Amplification System with Dendritic Bioreducible Polymer for the Treatment of Type 2 Diabetes. J. Gene Ther. 1(1): 7-15.
Ji-Kan Ryu*, Minhyung Lee*, Min Ji Choi, Hyun Ah Kim, Hai-Rong Jin, Woo Jean Kim, Guo Nan Yin, Kang-Moon Song, Mi-Hye Kwon, and Jun-Kyu Suh (2012) Gene Therapy with an Erythropoietin Enhancer-Mediated Hypoxia-Inducible Gene Expression System in the Corpus Cavernosum of Mice with High-Cholesterol Diet-Induced Erectile Dysfunction. J. Androl. 33(5): 845-853 (*Co-first authors).
Simmyung Yook, Jee-Heon Jeong, Yoon Suk Jung, Sung Woo Hong, Bok Hyeon Im, Jin Won Seo, Jun Beom Park, Minhyung Lee, Cheol-Hee Ahn, Haeshin Lee, Dong Yun Lee, and Youngro Byun (2012) Molecularly engineered islet cell clusters for diabetes mellitus treatment. Cell Transplant. 21(8): 1775-1789.
Jin Young Kim, Jae Hwan Ryu, Hyesun Hyun, Hyun Ah Kim, Joon Sig Choi, Dong Yun Lee, Taiyoun Rhim, Jeong Hyun Park*, and Minhyung Lee* (2012) Dexamethasone Conjugation to Polyamidoamine Dendrimers G1 and G2 for Enhanced Transfection Efficiency with an Anti-inflammatory Effect. J. Drug Target. 20(8):667-677. (*Co-corresponding authors)
Ji Hwan Park, Hyun Ah Kim, Jin Hyeong Park, and Minhyung Lee (2012) Amphiphilic peptide carrier for the combined delivery of curcumin and plasmid DNA into the lungs. Biomaterials. 33(27): 6542-6550.
Dong-Wook Ryu, Hyun Ah Kim, Soonhag Kim, and Minhyung Lee (2012) VEGF receptor binding peptide-linked amphiphilic peptide with arginines and valines for endothelial cell-specific gene delivery. J. Drug Target. 20(7): 574-581.
Ji Hwan Park, Hyun Ah Kim, Su Hee Cho, and Minhyung Lee (2012) Characterization of hydrophobic anti-cancer drug-loaded amphiphilic peptides as a gene carrier. J. Cell. Biochem. 113(5):1645-1653.
Dong-Wook Ryu, Hyun Ah Kim, Jae Hwa Ryu, Dong Yun Lee and Minhyung Lee (2012) Amphiphilic peptides with arginine and valine residues as siRNA carriers. J. Cell. Biochem. 113(2): 619-628.
Sanghyun Lee, Hojung Song, Hyun Ah Kim, Binna Oh, Dong Yun Lee, and Minhyung Lee (2012) The box A domain of high mobility group box-1 protein as an efficient siRNA carrier with anti-inflammatory effects. J. Cell. Biochem. 113(1): 122-131.
Jiyoung Lee, Hyesun Hyun, Jinyoung Kim, Jae Hwan Ryu, Hyun Ah Kim, Ji Hwan Park, and Minhyung Lee (2012) Dexamethasone-loaded peptide micelles for delivery of the heme oxygenase-1 gene to ischemic brain. J. Control. Release 158(1):131-138.
Young-Wook Won, Minhyung Lee, Hyun Ah Kim, David A. Bull, and Sung Wan Kim (2012) Post-translational regulated and hypoxia-responsible VEGF plasmid for efficient secretion. J. Control. Release 160(3): 525-531.
Youngsook Lee, Hye Yeong Nam, Jaesung Kim, Minhyung Lee, James W Yockman, Sug Kyun Shin, and Sung Wan Kim (2012) Human erythropoietin gene delivery using an arginine-grafted bioreducible polymer system. Mol. Ther. 20(7): 1360-1366.
Pyung-Hwan Kim, Minhyung Lee, and Sung Wan Kim (2012) Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model. J. Control. Release. 162: 9-18.
Hye Yeong Nam, Kihoon Nam, Minhyung Lee, Sung Wan Kim, and David A. Bull (2012) Dendrimer type bio-reducible polymer for efficient gene delivery. J. Control. Release 160(3): 592-600.
Jee-Heon Jeong, Simmyung Yook, Yoonsuk Jung, Bok-Hyeon Im, Minhyung Lee, Cheol-Hee Ahn, Dong Yun Lee, and Youngro Byun (2012) Functional enhancement of beta cells in transplanted pancreatic islets by secretion signal peptide-linked exendin-4 gene transduction. J. Control. Release 159(3): 368-375.
Hee Young Chae, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, Minhyung Lee, Dongchul Kang, Hee-Sook Jun, and Sung-Hee Ihm (2012) Effect of glucagon-like peptide-1 gene expression on graft function in mouse islet transplantation. Transplant Int. 25(2): 122-131.
Hye Yeong Nam, Youngsook Lee, Minhyung Lee, Sug Kyun Shin, Tae-il Kim, Sung Wan Kim, and David A. Bull (2012) Erythropoietin gene delivery using an arginine-grafted bioreducible polymer system. J. Control. Release 157(3): 437-444.
Hee Seok Yang, Jooyeon Park, Wan Geun La, Hyeon-ki Jang, Minhyung Lee, and Byung-Soo Kim (2012) 3,4-Dihydroxyphenylalanine-assisted hydroxyapatite nanoparticle coating on polymer scaffolds for efficient osteoconduction. Tisue Eng. Part C Methods. 18(4): 245-251.
Tai-il Kim, Minhyung Lee, and Sung Wan Kim (2012) Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer. J. Control. Release 157(2): 243-248.
Jin Kyeoung Kim, Kyung-Ju Choi, Minhyung Lee, Mi-hee Jo, and Soonhag Kim (2012) Molecular Imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle. Biomaterials 33(1): 207-217.
Hyun Ah Kim, Ji Hwan Park, Sanghyun Lee, Joon Sig Choi, Taeyoun Rhim, and Minhyung Lee (2011) Combined delivery of dexamethasone and plasmid DNA in an animal model of LPS-induced acute lung injury. J. Control. Release 156(1): 60-69.
Hyun Ah Kim, Taiyoun Rhim, Minhyung Lee (2011) Regulatory systems for hypoxia-inducible gene expression in ischemic heart disease gene therapy. Adv. Drug Deliv. Rev. 63(8): 678-687.
Hyun Ah Kim, Ji Hwan Park, Su Hee Cho, and Minhyung Lee (2011) Lung epithelial binding peptide-linked high mobility group box-1 A box for lung epithelial cell-specific delivery of DNA. J. Drug Target. 19(7): 589-596.
Dong-Wook Ryu, Hyun Ah Kim, Hojung Song, Soonhag Kim, and Minhyung Lee (2011) Amphiphilic peptides with arginines and valines for the delivery of plasmid DNA. J. Cell. Biochem. 112(5): 1458-1466.
Hyesun Hyun, Jiyoung Lee, Do Won Hwang, Soonhag Kim, Dong Keun Hyun, Joon Sig Choi, Ja-kyeong Lee, and Minhyung Lee (2011) Combinational therapy of ischemic brain stroke by delivery of heme oxygenase-1 gene and dexamethasone. Biomaterials 32: 306-315.
Woung-Wook Won, Kyung-Min Kim, Sung Sun An, Minhyung Lee, Yoon Ha, and Yong-Hee Kim (2011) Suicide gene therapy using reducible poly (oligo-D-arginine) for the treatment of spinal cord tumors. Biomaterials 32(36): 9766-9775.
Seung-Woo Kim, Chae-Moon Lim, Jung-Bin Kim, Joo-Hyun Shin, Sanghyun Lee, Minhyung Lee, and Ja-Kyeong Lee (2011) Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK singaling pathway. Neurotox. Res. 20(2): 159-169.
Hong Lian Jin, William A. Pennant, Minhyung Lee, Sung Su An, Hyun Ah Kim, Meng Lu Liu, Jin Soo Oh, Joon Cho, Keung Nyun Kim, Do Heum Yoon, Yoon Ha (2011) Neural stem cells modified by a hypoxia-inducible VEGF gene expression system improve cell viability under hypoxic conditions and spinal cord injury. Spine. 36(11): 857-864.
Hee Seok Yang, Wan-Geun La, Suk Ho Bhang, Tae-Jin Lee, Minhyung Lee, and Byung-Soo Kim (2011) Apatite-Coated Collagen Scaffold for Bone Morphogenetic Protein-2 Delivery. Tissue Eng. Part A. 17(17-18): 2153-2164.
Byung Wan Lee*, Minhyung Lee*, Hee Young Chae, Sanghyun Lee, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, Hyung Joon Yoo, and Sung-Hee Ihm (2011) Effect of hypoxia-inducible VEGF gene expression on revascularization and graft function in mouse islet transplantation. Transpl. Int. 24(3): 307-314. (*Co-first author).
Suk Ho Bhang, Ju Hee Kim, Hee Seok Yang, Wan-Geun La, Tae-Jin Lee, Ga Hee Kim, Hyun Ah Kim, Minhyung Lee, Byung-Soo Kim. (2011) Combined Gene Therapy with Hypoxia-Inducible Factor-1α and Heme Oxygenase-1 for Therapeutic Angiogenesis. Tissue Eng. Part A. 17(7-8): 915-926.
Sun Hwa Kim, Hyung-Ho Moon, Hyun Ah Kim, Ki-Chul Hwang, Minhyung Lee and Donghoon Choi (2011) Hypoxia-inducible vascular endothelial growth factor-engineered mesenchymal stem cells prevent myocardial ischemic injury. Mol. Ther. 19(4): 741-750.
Yin-Chuan Jin, Seung-Woo Kim, Felice Cheng, Joo-Hyun Shin, Jin-Kuen Park, Sanghyun Lee, Jung-Eun Lee, Pyung-Lim Han, Minhyung Lee, Kyekyoon (Kevin) Kim, Hyungsoo Choi, and Ja-Kyeong Lee. (2011) The effect of biodegradable gelatin microspheres on the neuroprotective effects of high mobility group box 1 A box in the postischemic brain. Biomaterials 32: 899-908.
Tae-Hun Kim, Gwang Sig Yu, Hye Choi, Young Jung Shim, Minhyung Lee, and Joog Sig Choi (2011) Preparation of dexamethasone-based cationic liposome and its application to gene delivery in vitro. J. Nanosci. Nanotech. 11(2): 1799-1802.