Department of Bioengineering, Hanyang University




허혈성 뇌졸중 유전자 및 단백질 치료 연구
유전자 전달체 개발


  1. Gyeungyun Kim, Chunxian Piao, Jungju Oh, and Minhyung Lee (2018) Self-assembled polymeric micelles for combined delivery of anti-inflammatory gene and drug to the lungs by inhalation. Nanoscale. 18: 8503-8514.
  2. Eunji Choi, Jungju Oh, Dahee Lee, Jaewon Lee, Xiaonan Tan, Minhyung Kim, Gyeungyun Kim, Chunxian Piao, and Minhyung Lee (2018) A ternary-complex of a suicide gene, a RAGE-binding peptide, and polyethylenimine as a gene delivery system with anti-tumor and anti-angiogenic dual effects in glioblastoma. J. Control. Release 279: 40-52.
  3. Xiaonan Tan, Gyeungyun Kim, Dahee Lee, Jungju Oh, Minkyung Kim, Chunxian Piao, Jaewon Lee, Min Sang Lee, Ji Hoon Jeong, and Minhyung Lee (2018) A curcumin-loaded polymeric micelle as a carrier of a microRNA-21 antisense-oligonucleotide for enhanced anti-tumor effects in a glioblastoma animal model. Biomater. Sci. 6: 407-417.
  4. Jungju Oh, Min Sang Lee, Ji Hoon Jeong*, and Minhyung Lee* (2017) Deoxycholic Acid-Conjugated Polyethylenimine for Delivery of Heme Oxygenase-1 Gene in Rat Ischemic Stroke Model. J. Pharm. Sci. 106(12): 3524-3532.
  5. Minhyung Lee, Min Jun Kim, Jungju Oh, Chunxian Piao, Young-Woo Park, and Dong Yun Lee (2017) Gene delivery to pancreatic islets for effective transplantation in diabetic animal. J. Ind. Eng. Chem. 56: 45-54.
  6. Eunji Choi, Jaesik Han, Xiaonan Tan, Jungju Oh, Dahee Lee, Taiyoun Rhim*, and Minhyung Lee* (2017) Combined delivery of temozolomide and the thymidine kinase gene for treatment of glioblastoma. J. Drug Target. 25(2): 156-162.
  7. Binna Oh, Hojung Song, Dahee Lee, Jungju Oh, Gyeungyun Kim, Sung-Hee Ihm*, and Minhyung Lee* (2016) Anti-cancer effect of R3V6 peptide-mediated delivery of an anti-microRNA-21 antisense-oligodeoxynucleotide in a glioblastoma animal model. J. Drug Target. 25(2): 132-139.
  8. Manbok Choi, Jungju Oh, Taiyoun Rhim*, and Minhyung Lee* (2016) Delivery of hypoxia-inducible heme oxygenase-1 gene for site-specific gene therapy in the ischemic stroke animal model. Pharm. Res. 33(9): 2250-2258.
  9. Jaesik Han, Jungju Oh, Sung-Hee Ihm*, and Minhyung Lee* (2016) Peptide micelle-mediated cur cumin delivery for protection of islet beta-cells under hypoxia. J. Drug Target. 24(7): 618-623.
  10. Pureum Jeon, Manbok Choi, Jungju Oh, and Minhyung Lee (2015) Dexamethasone-conjugated polyamidoamine dendrimer for delivery of the heme oxygenase-1 gene into the ischemic brain. Macromol. Biosci. 15(7): 1021-1028.